Cyclical Variations of Blood Concentration of Phenytoin and Its Pharmacokinetics in Menstrual Epilepsy 经期性癫痫苯妥英血药浓度及药动学的周期性变化
Aim: To study effects of estrogen on GABA and P38 in the hippocampus of menstrual epilepsy rats, and this will supply the basis for the mechanisms that estrogen enhances epileptic seizures. 目的:分析月经性癫痫中,雌激素对大鼠海马内γ-氨基丁酸(γ-amiobutyricacid,GABA)和P38的影响,探讨雌激素促癫痫发作的作用机理。